Expression profiling and in situ screening of circular RNAs in human tissues.
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ABSTRACT:
SUBMITTER: Zaghlool A
PROVIDER: S-EPMC6240052 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Expression profiling and in situ screening of circular RNAs in human tissues.
Zaghlool Ammar A Ameur Adam A Wu Chenglin C Westholm Jakub Orzechowski JO Niazi Adnan A Manivannan Manimozhi M Bramlett Kelli K Nilsson Mats M Feuk Lars L
Scientific reports 20181116 1
Circular RNAs (circRNAs) were recently discovered as a class of widely expressed noncoding RNA and have been implicated in regulation of gene expression. However, the function of the majority of circRNAs remains unknown. Studies of circRNAs have been hampered by a lack of essential approaches for detection, quantification and visualization. We therefore developed a target-enrichment sequencing method suitable for screening of circRNAs and their linear counterparts in large number of samples. We ...[more]
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