Immune checkpoint inhibitor-related acral vasculitis.
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ABSTRACT:
SUBMITTER: Comont T
PROVIDER: S-EPMC6240222 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Immune checkpoint inhibitor-related acral vasculitis.
Comont Thibault T Sibaud Vincent V Mourey Loïc L Cougoul Pierre P Beyne-Rauzy Odile O
Journal for immunotherapy of cancer 20181116 1
Commentary on « Ipilimumab induced vasculitis » by Padda A. et al., J Immunother Cancer. 2018;6:12. The authors diagnosed a small vessel vasculitis following treatment with anti-CTLA-4 (ipilimumab) for a resected stage III B/C melanoma. We report a similar case of acral vasculitis occurring with a combination of anti-CTLA-4 (tremelimumab) and anti-PD-L1 (durvalumab) prescribed for the management of a metastatic urothelial bladder cancer. In contrast to Padda A. et al., we observed a significant ...[more]
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