Ontology highlight
ABSTRACT:
SUBMITTER: Chernaya O
PROVIDER: S-EPMC6240601 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
iScience 20181104
At early stages of organismal development, endothelial cells self-organize into complex networks subsequently giving rise to mature blood vessels. The compromised collective behavior of endothelial cells leads to the development of a number of vascular diseases, many of which can be life-threatening. Cerebral cavernous malformation is an example of vascular diseases caused by abnormal development of blood vessels in the brain. Despite numerous efforts to date, enlarged blood vessels (cavernomas) ...[more]