Ontology highlight
ABSTRACT:
SUBMITTER: Potabattula R
PROVIDER: S-EPMC6240887 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Epigenomics 20180921 10
<h4>Aim</h4>To examine the effects of genetic variation, parental age and BMI on parental allele-specific methylation of imprinted genes in fetal cord blood samples.<h4>Methodology</h4>We have developed SNP genotyping and deep bisulphite sequencing assays for six imprinted genes to determine parental allele-specific methylation patterns in diploid somatic tissues.<h4>Results</h4>Multivariate linear regression analyses revealed a negative correlation of paternal age with paternal MEG3 allele meth ...[more]