Ontology highlight
ABSTRACT:
SUBMITTER: Haridas M
PROVIDER: S-EPMC6244999 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Haridas Meera M Abdelraheem Eman M M EMM Hanefeld Ulf U
Applied microbiology and biotechnology 20181003 23
2-Deoxy-D-ribose-5-phosphate aldolase (DERA) is a class I aldolase that offers access to several building blocks for organic synthesis. It catalyzes the stereoselective C-C bond formation between acetaldehyde and numerous other aldehydes. However, the practical application of DERA as a biocatalyst is limited by its poor tolerance towards industrially relevant concentrations of aldehydes, in particular acetaldehyde. Therefore, the development of proper experimental conditions, including protein e ...[more]