GVHD: biology matters.
Ontology highlight
ABSTRACT:
SUBMITTER: Ferrara JLM
PROVIDER: S-EPMC6245966 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
GVHD: biology matters.
Ferrara James L M JLM Chaudhry Mohammed S MS
Hematology. American Society of Hematology. Education Program 20181101 1
Acute graft-versus-host disease (GVHD) targets the crypts in the gastrointestinal (GI) tract that are responsible for the self-renewal of the intestinal mucosa. Recent advances in the identification and culture of intestinal stem cells have improved our understanding of the interactions between the microbiome and the immune system (both innate and adaptive) that are key to the pathophysiology of GVHD. The identification of serum biomarkers that best predict long-term GVHD outcomes derive from th ...[more]
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