Ontology highlight
ABSTRACT:
SUBMITTER: Amoroso N
PROVIDER: S-EPMC6247675 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Amoroso Nicola N La Rocca Marianna M Bruno Stefania S Maggipinto Tommaso T Monaco Alfonso A Bellotti Roberto R Tangaro Sabina S
Frontiers in aging neuroscience 20181114
Analysis and quantification of brain structural changes, using Magnetic Resonance Imaging (MRI), are increasingly used to define novel biomarkers of brain pathologies, such as Alzheimer's disease (AD). Several studies have suggested that brain topological organization can reveal early signs of AD. Here, we propose a novel brain model which captures both intra- and inter-subject information within a multiplex network approach. This model localizes brain atrophy effects and summarizes them with a ...[more]