Ontology highlight
ABSTRACT:
SUBMITTER: Hung WT
PROVIDER: S-EPMC6248580 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Hung Wei-Ting WT Navakanitworakul Raphatphorn R Khan Tarique T Zhang Pan P Davis John S JS McGinnis Lynda K LK Christenson Lane K LK
Biology of reproduction 20171001 4
Follicular fluid within ovarian antral follicles contains numerous factors, which influence the development of a healthy oocyte including nucleic acids, steroids, proteins, and extracellular vesicles (EVs). Current evidence indicates that follicular EVs promote changes in cellular gene expression and support cumulus-oocyte complex expansion in vitro. In this study, we found EVs from different sized follicles differentially stimulate granulosa cell proliferation and this could be explained by bot ...[more]