Ontology highlight
ABSTRACT:
SUBMITTER: Rosenke K
PROVIDER: S-EPMC6249563 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
The Journal of infectious diseases 20181101 suppl_5
Antibody therapy has been used to treat a variety of diseases and the success of ZMapp and other monoclonal antibody-based therapies during the 2014-2016 West African Ebola outbreak has shown this countermeasure can be a successful therapy for Ebola hemorrhagic fever. This study utilized transchromosomal bovines (TcB) vaccinated with a DNA plasmid encoding Ebola virus glycoprotein sequence to produce human polyclonal antibodies directed against Ebola virus glycoprotein. When administered 1 day p ...[more]