Ontology highlight
ABSTRACT:
SUBMITTER: Patel SR
PROVIDER: S-EPMC6250814 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Patel Seema R SR Gibb David R DR Girard-Pierce Kathryn K Zhou Xiaoxi X Rodrigues Lilian Cataldi LC Arthur Connie M CM Bennett Ashley L AL Jajosky Ryan P RP Fuller Megan M Maier Cheryl L CL Zerra Patricia E PE Chonat Satheesh S Smith Nicole H NH Tormey Christopher A CA Hendrickson Jeanne E JE Stowell Sean R SR
Frontiers in immunology 20181116
Red blood cell (RBC) alloimmunization represents a significant immunological challenge for some patients. While a variety of immune constituents likely contribute to the initiation and orchestration of alloantibodies to RBC antigens, identification of key immune factors that initiate alloantibody formation may aid in the development of a therapeutic modality to minimize or prevent this process. To define the immune factors that may be important in driving alloimmunization to an RBC antigen, we d ...[more]