Ontology highlight
ABSTRACT:
SUBMITTER: Stachowicz A
PROVIDER: S-EPMC6251889 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Stachowicz Aneta A Zabczyk Michal M Natorska Joanna J Suski Maciej M Olszanecki Rafał R Korbut Ryszard R Wiśniewski Jacek R JR Undas Anetta A
Scientific reports 20181123 1
The prothrombotic fibrin clot phenotype has been reported in patients with thrombotic antiphospholipid syndrome (APS) and venous thromboembolism (VTE). Protein composition of plasma fibrin clots in APS has not been studied. We evaluated 23 patients with thrombotic APS, 19 with VTE alone, and 20 well-matched controls. A proteomic analysis of fibrin clots generated from citrated plasma was based on liquid chromatography-mass spectrometry. Plasma levels of thrombospondin-1 (TSP1), apolipoprotein(a) ...[more]