Reduced higher-dimensional resting state fMRI dynamism in clinical high-risk individuals for schizophrenia identified by meta-state analysis.
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ABSTRACT:
SUBMITTER: Mennigen E
PROVIDER: S-EPMC6252113 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Reduced higher-dimensional resting state fMRI dynamism in clinical high-risk individuals for schizophrenia identified by meta-state analysis.
Mennigen Eva E Miller Robyn L RL Rashid Barnaly B Fryer Susanna L SL Loewy Rachel L RL Stuart Barbara K BK Mathalon Daniel H DH Calhoun Vince D VD
Schizophrenia research 20180612
New techniques to investigate functional network connectivity in resting state functional magnetic resonance imaging data have recently emerged. One novel approach, called meta-state analysis, goes beyond the mere cross-correlation of time courses of distinct brain areas and explores temporal dynamism in more detail, allowing for connectivity states to overlap in time and capturing global dynamic behavior. Previous studies have shown that patients with chronic schizophrenia exhibit reduced neura ...[more]
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