Ontology highlight
ABSTRACT:
SUBMITTER: Rivera-Oliver M
PROVIDER: S-EPMC6252157 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Rivera-Oliver Marla M Moreno Estefanía E Álvarez-Bagnarol Yocasta Y Ayala-Santiago Christian C Cruz-Reyes Nicole N Molina-Castro Gian Carlo GC Clemens Stefan S Canela Enric I EI Ferré Sergi S Casadó Vicent V Díaz-Ríos Manuel M
Molecular neurobiology 20180524 2
While the role of the ascending dopaminergic system in brain function and dysfunction has been a subject of extensive research, the role of the descending dopaminergic system in spinal cord function and dysfunction is just beginning to be understood. Adenosine plays a key role in the inhibitory control of the ascending dopaminergic system, largely dependent on functional complexes of specific subtypes of adenosine and dopamine receptors. Combining a selective destabilizing peptide strategy with ...[more]