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ABSTRACT: Objective
To investigate UK healthcare professionals' perceptions and perspectives towards biosimilar infliximab, etanercept and insulin glargine and the potential barriers and facilitators to their prescribing.Design
A cross-sectional qualitative study design was used.Setting
Five hospitals within the West Midlands area in UK.Interventions
30?min face-to-face, semistructured interviews of healthcare professionals.Participants
22 healthcare professionals (consultants, nurses and pharmacists) participated in the semistructured interviews.Outcomes
Participants' opinion and attitudes about biosimilars and the barriers and facilitators to the prescribing of infliximab, etanercept and insulin glargine biosimilars in gastroenterology, rheumatology and diabetology specialties.Results
This study showed that UK healthcare professionals had good knowledge of biosimilars and were content to initiate them. Healthcare professionals disagreed with biosimilar auto-substitution at pharmacy level and multiple switching. Subtle differences among healthcare professionals were identified in the acceptance of switching stable patients, indication extrapolation and cost savings sharing.Conclusion
Safety and efficacy concerns, patients' opinion and how cost savings were shared were the identified barriers to considering prescribing biosimilars. Real-life data and financial incentives were the suggested facilitators to increase biosimilar utilisation.
SUBMITTER: Aladul MI
PROVIDER: S-EPMC6252648 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Aladul Mohammed Ibrahim MI Fitzpatrick Raymond William RW Chapman Stephen Robert SR
BMJ open 20181118 11
<h4>Objective</h4>To investigate UK healthcare professionals' perceptions and perspectives towards biosimilar infliximab, etanercept and insulin glargine and the potential barriers and facilitators to their prescribing.<h4>Design</h4>A cross-sectional qualitative study design was used.<h4>Setting</h4>Five hospitals within the West Midlands area in UK.<h4>Interventions</h4>30 min face-to-face, semistructured interviews of healthcare professionals.<h4>Participants</h4>22 healthcare professionals ( ...[more]