Corneal Confocal Microscopy detects a Reduction in Corneal Endothelial Cells and Nerve Fibres in Patients with Acute Ischemic Stroke.
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ABSTRACT:
SUBMITTER: Khan A
PROVIDER: S-EPMC6255787 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
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Corneal Confocal Microscopy detects a Reduction in Corneal Endothelial Cells and Nerve Fibres in Patients with Acute Ischemic Stroke.
Khan Adnan A Kamran Saadat S Akhtar Naveed N Ponirakis Georgios G Al-Muhannadi Hamad H Petropoulos Ioannis N IN Al-Fahdawi Shumoos S Qahwaji Rami R Sartaj Faheem F Babu Blessy B Wadiwala Muhammad Faisal MF Shuaib Ashfaq A Malik Rayaz A RA
Scientific reports 20181126 1
Endothelial dysfunction and damage underlie cerebrovascular disease and ischemic stroke. We undertook corneal confocal microscopy (CCM) to quantify corneal endothelial cell and nerve morphology in 146 patients with an acute ischemic stroke and 18 age-matched healthy control participants. Corneal endothelial cell density was lower (P < 0.001) and endothelial cell area (P < 0.001) and perimeter (P < 0.001) were higher, whilst corneal nerve fibre density (P < 0.001), corneal nerve branch density (P ...[more]
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