Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC6255913 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Li Xinzhong X Wang Haiyan H Long Jintao J Pan Genhua G He Taigang T Anichtchik Oleg O Belshaw Robert R Albani Diego D Edison Paul P Green Elaine K EK Scott James J
Scientific reports 20181126 1
Revealing the relationship between dysfunctional genes in blood and brain tissues from patients with Alzheimer's Disease (AD) will help us to understand the pathology of this disease. In this study, we conducted the first such large systematic analysis to identify differentially expressed genes (DEGs) in blood samples from 245 AD cases, 143 mild cognitive impairment (MCI) cases, and 182 healthy control subjects, and then compare these with DEGs in brain samples. We evaluated our findings using t ...[more]