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An intensive milk replacer feeding program benefits immune response and intestinal microbiota of lambs during weaning.

ABSTRACT: BACKGROUND:Pre-weaning milk replacer (MR) feeding program is a key factor affecting the health and welfare of lambs during their weaning. Weaning stress is well known as an inducement that negatively impacts the immune system of young ruminants, whose physiological and immune state is closely linked to the community of microbiota in their intestines. This study had two objectives: 1) To evaluate the innate immune response to weaning stress at both the physiological and molecular level; 2) To investigate changes to the jejunal chyme and mucosal adhesive microbiota between the control and high plane of MR groups. RESULTS:In this experiment, the plasma concentrations of cortisol, norepinephrine (NE) and tumor necrosis factor-? (TNF?) were higher in the C than the H group (P?

SUBMITTER: Zhang Q

PROVIDER: S-EPMC6258415 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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An intensive milk replacer feeding program benefits immune response and intestinal microbiota of lambs during weaning.

Zhang Qian Q Li Chong C Niu Xiaolin X Zhang Zhian Z Li Fadi F Li Fei F

BMC veterinary research 20181126 1

<h4>Background</h4>Pre-weaning milk replacer (MR) feeding program is a key factor affecting the health and welfare of lambs during their weaning. Weaning stress is well known as an inducement that negatively impacts the immune system of young ruminants, whose physiological and immune state is closely linked to the community of microbiota in their intestines. This study had two objectives: 1) To evaluate the innate immune response to weaning stress at both the physiological and molecular level; 2 ...[more]

PMID: 30477479

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