Ontology highlight
ABSTRACT:
SUBMITTER: Mehta S
PROVIDER: S-EPMC6258557 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Mehta Sohum S Zhang Yong Y Roth Richard H RH Zhang Jin-Fan JF Mo Albert A Tenner Brian B Huganir Richard L RL Zhang Jin J
Nature cell biology 20180924 10
Unravelling the dynamic molecular interplay behind complex physiological processes such as neuronal plasticity requires the ability to both detect minute changes in biochemical states in response to physiological signals and track multiple signalling activities simultaneously. Fluorescent protein-based biosensors have enabled the real-time monitoring of dynamic signalling processes within the native context of living cells, yet most commonly used biosensors exhibit poor sensitivity (for example, ...[more]