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Synthesis and Reactivity of [1,2,4]Triazolo-annelated Quinazolines


ABSTRACT: This paper reports the synthesis of phenyl-substituted 2-alkoxy(methylsulfanyl)-1,2,4-triazolo[1,5-a]quinazolines starting from N-cyanoimidocarbonates and substituted hydrazinobenzoic acids as building blocks. Thionation or chlorination of the inherent lactam moiety in the target compounds followed by treatment with multifunctional nucleophiles provided access to a variety of derivatives.

SUBMITTER: Al-Salahi R 

PROVIDER: S-EPMC6259257 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

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