Ontology highlight
ABSTRACT:
SUBMITTER: Abrosimova LA
PROVIDER: S-EPMC6261011 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Abrosimova Liudmila A LA Migur Anzhela Yu AY Kubareva Elena A EA Zatsepin Timofei S TS Gavshina Aleksandra V AV Yunusova Alfiya K AK Perevyazova Tatiana A TA Pingoud Alfred A Oretskaya Tatiana S TS
PloS one 20181126 11
Nicking endonucleases (NEases) selectively cleave single DNA strands in double-stranded DNAs at a specific site. They are widely used in bioanalytical applications and in genome editing; however, the peculiarities of DNA-protein interactions for most of them are still poorly studied. Previously, it has been shown that the large subunit of heterodimeric restriction endonuclease BspD6I (Nt.BstD6I) acts as a NEase. Here we present a study of interaction of restriction endonuclease BspD6I with modif ...[more]