Ontology highlight
ABSTRACT:
SUBMITTER: Vermesh O
PROVIDER: S-EPMC6261517 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Vermesh Ophir O Aalipour Amin A Ge T Jessie TJ Saenz Yamil Y Guo Yue Y Alam Israt S IS Park Seung-Min SM Adelson Charlie N CN Mitsutake Yoshiaki Y Vilches-Moure Jose J Godoy Elias E Bachmann Michael H MH Ooi Chin Chun CC Lyons Jennifer K JK Mueller Kerstin K Arami Hamed H Green Alfredo A Solomon Edward I EI Wang Shan X SX Gambhir Sanjiv S SS
Nature biomedical engineering 20180716 9
The detection and analysis of rare blood biomarkers is necessary for early diagnosis of cancer and to facilitate the development of tailored therapies. However, current methods for the isolation of circulating tumour cells (CTCs) or nucleic acids present in a standard clinical sample of only 5-10 ml of blood provide inadequate yields for early cancer detection and comprehensive molecular profiling. Here, we report the development of a flexible magnetic wire that can retrieve rare biomarkers from ...[more]