Ontology highlight
ABSTRACT:
SUBMITTER: Vukelic M
PROVIDER: S-EPMC6262343 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Vukelic Milena M Li Yi Y Kyttaris Vasileios C VC
Frontiers in immunology 20181116
<h4>Purpose of review</h4>The standard treatment options for systemic lupus erythematosus (SLE) are focused on non-specific immunosuppression. Over the past few years, scientific studies and ongoing clinical trials have shifted the paradigm with rapid advances in developing biologics and small molecules. A number of monoclonal antibodies and small molecule inhibitors have been developed to target specific pathways involved in SLE. Many of these novel therapeutic agents are already being tested i ...[more]