Ontology highlight
ABSTRACT:
SUBMITTER: Bruce L
PROVIDER: S-EPMC6262642 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Bruce Lindsay L Singkornrat Diana D Wilson Kelsey K Hausman William W Robbins Kelli K Huang Lingxi L Foss Katie K Binninger David D
Antioxidants (Basel, Switzerland) 20181101 11
The deleterious alteration of protein structure and function due to the oxidation of methionine residues has been studied extensively in age-associated neurodegenerative disorders such as Alzheimer's and Parkinson's Disease. Methionine sulfoxide reductases (MSR) have three well-characterized biological functions. The most commonly studied function is the reduction of oxidized methionine residues back into functional methionine thus, often restoring biological function to proteins. Previous studi ...[more]