4D-QSAR: perspectives in drug design.
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ABSTRACT:
SUBMITTER: Andrade CH
PROVIDER: S-EPMC6263259 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Publications
4D-QSAR: perspectives in drug design.
Andrade Carolina H CH Pasqualoto Kerly F M KF Ferreira Elizabeth I EI Hopfinger Anton J AJ
Molecules (Basel, Switzerland) 20100504 5
Drug design is a process driven by innovation and technological breakthroughs involving a combination of advanced experimental and computational methods. A broad variety of medicinal chemistry approaches can be used for the identification of hits, generation of leads, as well as to accelerate the optimization of leads into drug candidates. The quantitative structure-activity relationship (QSAR) formalisms are among the most important strategies that can be applied for the successful design new m ...[more]
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