Dietary patterns, bone lead and incident coronary heart disease among middle-aged to elderly men.

ABSTRACT:

Background

Most absorbed lead ends up in the bone, where it can be measured as a biomarker of cumulative exposure, elevations of which have been shown to predict a higher risk of coronary heart disease (CHD). Knowledge about the role of dietary patterns is critical to the development of effective interventions for the cardiovascular toxicity of cumulative lead exposure.

Methods

594 men, free of CHD at baseline, were followed from August 1991 to June 2011 in the Normative Aging Study. Bone lead concentrations were measured by K-shell-X-ray fluorescence. Dietary patterns were identified using principal components analysis. Two dietary patterns were identified: a 'prudent' pattern characterized by high intake of fruit, vegetables, legumes, tomatoes, poultry, and seafood; and a

SUBMITTER: Ding N 

PROVIDER: S-EPMC6263823 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature