Intramolecular C-H···O hydrogen bonding in 1,4-dihydropyridine derivatives.
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ABSTRACT:
SUBMITTER: Petrova M
PROVIDER: S-EPMC6264772 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Publications
Intramolecular C-H···O hydrogen bonding in 1,4-dihydropyridine derivatives.
Petrova Marina M Muhamadejev Ruslan R Vigante Brigita B Cekavicus Brigita B Plotniece Aiva A Duburs Gunars G Liepinsh Edvards E
Molecules (Basel, Switzerland) 20110919 9
The diastereotopy of the methylene protons at positions 2 and 6 in 1,4-dihydropiridine derivatives with various substituents has been investigated. NMR spectroscopy and quantum chemistry calculations show that the CH···O intramolecular hydrogen bond is one of the factors amplifying the chemical shift differences in the 1H-NMR spectra. ...[more]
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