Ontology highlight
ABSTRACT:
SUBMITTER: Fairweather JK
PROVIDER: S-EPMC6268951 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Fairweather Jon K JK Liu Ligong L Karoli Tomislav T Ferro Vito V
Molecules (Basel, Switzerland) 20120815 8
A 6-deoxy-α-L-talopyranoside acceptor was readily prepared from methyl α-L-rhamnopyranoside and glycosylated with thiogalactoside donors using NIS/TfOH as the promoter to give good yields of the desired a-linked disaccharide (69-90%). Glycosylation with a 2-azido-2-deoxy-D-glucosyl trichloroacetimidate donor was not completely stereoselective (α:β = 6:1), but the desired a-linked disaccharide could be isolated in good overall yield (60%) following conversion into its corresponding tribenzoate de ...[more]