Ontology highlight
ABSTRACT:
SUBMITTER: Arenas P
PROVIDER: S-EPMC6270201 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20130816 8
A broad variety of oxygen-substituted diaryl ketones has been synthesized by solar energy-induced Friedel Crafts acylations of 1,4-benzo- and 1,4-naphthoquinones with benzaldehydes. The in vitro antiproliferative properties of the photoproducts were assessed on prostate (DU-145), bladder (T24) and breast (MCF7) human-derived tumor cell lines and compared to non-tumor mouse fibroblasts (Balb/3T3). Among the tested compounds, it was found that those containing a 3,4,5-trimethoxyphenyl A-ring, such ...[more]