Molecular Modeling to Study Dendrimers for Biomedical Applications.

ABSTRACT: Molecular modeling techniques provide a powerful tool to study the properties of molecules and their interactions at the molecular level. The use of computational techniques to predict interaction patterns and molecular properties can inform the design of drug delivery systems and therapeutic agents. Dendrimers are hyperbranched macromolecular structures that comprise repetitive building blocks and have defined architecture and functionality. Their unique structural features can be exploited to design novel carriers for both therapeutic and diagnostic agents. Many studies have been performed to iteratively optimise the properties of dendrimers in solution as well as their interaction with drugs, nucleic acids, proteins and lipid membranes. Key features including dendrimer size and surface

SUBMITTER: Martinho N 

PROVIDER: S-EPMC6270869 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature