Ontology highlight
ABSTRACT:
SUBMITTER: Chen LC
PROVIDER: S-EPMC6271468 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Chen Li-Chai LC Lin Yen-You YY Jean Yen-Hsuan YH Lu Yi Y Chen Wu-Fu WF Yang San-Nan SN Wang Hui-Min David HM Jang Ing-Yang IY Chen I-Ming IM Su Jui-Hsin JH Sung Ping-Jyun PJ Sheu Jyh-Horng JH Wen Zhi-Hong ZH
Molecules (Basel, Switzerland) 20140916 9
To date, no study has been conducted to explore the bioactivity of the crinoid Comanthus bennetti. Here we report the anti-inflammatory properties of comaparvin (5,8-dihydroxy-10-methoxy-2-propylbenzo[h]chromen-4-one) based on in vivo experiments. Our preliminary screening for anti-inflammatory activity revealed that the crude extract of Comanthus bennetti significantly inhibited the expression of pro-inflammatory proteins in lipopolysaccharide (LPS)-stimulated murine RAW 264.7 macrophage cells. ...[more]