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A new sesquilignan glucoside from Uraria sinensis.

ABSTRACT: A new sesquilignan glucoside, urariasinoside A (1), together with eight known compounds, including two lignans, a sesquilignan, a dilignan, and four flavonoid derivatives were isolated from the aerial parts of Uraria sinensis. Their structures were determined on the basis of extensive spectroscopic analyses and comparison with literature data. Compound 1 was evaluated for in vitro cytotoxicity activity against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines.

SUBMITTER: Yang Y

PROVIDER: S-EPMC6271682 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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A new sesquilignan glucoside from Uraria sinensis.

Yang Yingda Y Hu Zhengxi Z Luo Zengwei Z Xue Yongbo Y Yao Guangmin G Wang Yanyan Y Zhang Yonghui Y

Molecules (Basel, Switzerland) 20140117 1

A new sesquilignan glucoside, urariasinoside A (1), together with eight known compounds, including two lignans, a sesquilignan, a dilignan, and four flavonoid derivatives were isolated from the aerial parts of Uraria sinensis. Their structures were determined on the basis of extensive spectroscopic analyses and comparison with literature data. Compound 1 was evaluated for in vitro cytotoxicity activity against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines. ...[more]

PMID: 24445344

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