Ontology highlight
ABSTRACT:
SUBMITTER: El-Haggar R
PROVIDER: S-EPMC6272174 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20150326 4
Coumarin and their derivatives have drawn much attention in the pharmacological and pharmaceutical fields due to their broad range and diverse biological activities. In the present work, starting from the 6-amino-7-hydroxy-4-methyl-2H-chromen-2-one, a series of 6-(substituted benzylamino)-7-hydroxy-4-methyl-2H-chromen-2-ones 1-11 was synthesized and assessed for their anti-inflammatory activity using the carrageenan-induced hind paw edema method. Compounds 2, 3, 4 and 9 showed significant (p < 0 ...[more]