Ontology highlight
ABSTRACT:
SUBMITTER: Al-Sheddi ES
PROVIDER: S-EPMC6272518 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Al-Sheddi Ebtesam Saad ES Al-Oqail Mai Mohammad MM Saquib Quaiser Q Siddiqui Maqsood Ahmed MA Musarrat Javed J Al-Khedhairy Abdulaziz Ali AA Farshori Nida Nayyar NN
Molecules (Basel, Switzerland) 20150507 5
Owing to the pharmacological potential of ATRA (all trans-retinoic acid), a series of retinamides and a 1-(retinoyl)-1,3-dicyclohexylurea compound were prepared by reacting ATRA with long chain alkyl or alkenyl fatty amines by using a 4-demethylaminopyridine (DMAP)-catalyzed N,N¢-dicyclohexylcarbodiimide (DCC) coupling. The successful synthesis of the target compounds was demonstrated using a range of spectroscopic techniques. The cytotoxicity of the compounds was measured along with their abili ...[more]