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A trinuclear oxo-chromium(III) complex containing the natural flavonoid primuletin: synthesis, characterization, and antiradical properties.

ABSTRACT: A new trinuclear oxo-centered chromium(III) complex with formula [Cr3O(CH3CO2)6(L)(H2O)2] (L = 5-hydroxyflavone, known as primuletin) was synthetized and characterized by ESI mass spectrometry, thermogravimetry, and 1H-NMR, UV-Vis, and FTIR spectroscopies. In agreement with the experimental results, DFT calculations indicated that the flavonoid ligand is coordinated to one of the three Cr(III) centers in an O,O-bidentate mode through the 5-hydroxy/4-keto groups. In a comparative study involving the uncoordinated primuletin and its corresponding complex, systematic reactions with the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) showed that antiradical activity increases upon complexation.

SUBMITTER: Alexiou AD

PROVIDER: S-EPMC6272679 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature

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A trinuclear oxo-chromium(III) complex containing the natural flavonoid primuletin: synthesis, characterization, and antiradical properties.

Alexiou Anamaria D P AD Decandio Carla C CC Almeida Sabrina da N Sda N Ferreira Marcelo J P MJ Romoff Paulete P Rocha Reginaldo C RC

Molecules (Basel, Switzerland) 20150410 4

A new trinuclear oxo-centered chromium(III) complex with formula [Cr3O(CH3CO2)6(L)(H2O)2] (L = 5-hydroxyflavone, known as primuletin) was synthetized and characterized by ESI mass spectrometry, thermogravimetry, and 1H-NMR, UV-Vis, and FTIR spectroscopies. In agreement with the experimental results, DFT calculations indicated that the flavonoid ligand is coordinated to one of the three Cr(III) centers in an O,O-bidentate mode through the 5-hydroxy/4-keto groups. In a comparative study involving ...[more]

PMID: 25867822

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