Ontology highlight
ABSTRACT:
SUBMITTER: Kumar V
PROVIDER: S-EPMC6273029 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Kumar Vinod V Mathur Divya D Srivastava Smriti S Malhotra Shashwat S Rana Neha N Singh Suraj K SK Singh Brajendra K BK Prasad Ashok K AK Varma Anjani J AJ Len Christophe C Kuhad Ramesh C RC Saxena Rajendra K RK Parmar Virinder S VS
Molecules (Basel, Switzerland) 20161109 11
Highly regioselective acylation has been observed in 7,8-dihydroxy-4-methylcoumarin (DHMC) by the lipase from <i>Rhizopus oryzae</i> suspended in tetrahydrofuran (THF) at 45 °C using six different acid anhydrides as acylating agents. The acylation occurred regioselectively at one of the two hydroxy groups of the coumarin moiety resulting in the formation of 8-acyloxy-7-hydroxy-4-methylcoumarins, which are important bioactive molecules for studying biotansformations in animals, and are otherwise ...[more]