Dataset Information
Picrotoxane Sesquiterpene Glycosides and a Coumarin Derivative from Coriaria nepalensis and Their Neurotrophic Activity.
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ABSTRACT:
SUBMITTER: Wang YY
PROVIDER: S-EPMC6273530 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
Picrotoxane Sesquiterpene Glycosides and a Coumarin Derivative from Coriaria nepalensis and Their Neurotrophic Activity.
Molecules (Basel, Switzerland) 20161012 10
Two picrotoxane sesquiterpene lactone glycosides, nepalactones A (<b>1</b>) and B (<b>2</b>), and one new coumarin, nepalarin (<b>3</b>), were isolated from the root barks of the poisonous plant <i>Coriaria</i><i>nepalensis</i>. Their structures were elucidated via HRESIMS and 1D and 2D NMR spectroscopic analyses, and further verified via transformation methods. In addition, compounds <b>1</b>-<b>3</b> and five semisynthetic congeners (<b>1a</b>-<b>e</b>) were assayed for the activity to induce ...[more]
