Ontology highlight
ABSTRACT:
SUBMITTER: Yehye WA
PROVIDER: S-EPMC6273539 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Yehye Wageeh A WA Abdul Rahman Noorsaadah N Saad Omar O Ariffin Azhar A Abd Hamid Sharifah Bee SB Alhadi Abeer A AA Kadir Farkaad A FA Yaeghoobi Marzieh M Matlob Abdulsalam A AA
Molecules (Basel, Switzerland) 20160628 7
A new series of multipotent antioxidants (MPAOs), namely Schiff base-1,2,4-triazoles attached to the oxygen-derived free radical scavenging moiety butylated hydroxytoluene (BHT) were designed and subsequently synthesized. The structure-activity relationship (SAR) of the designed antioxidants was established alongside the prediction of activity spectra for substances (PASS). The antioxidant activities of the synthesized compounds 4-10 were tested by the DPPH bioassay. The synthesized compounds 4- ...[more]