Ontology highlight
ABSTRACT:
SUBMITTER: Bharathiraja S
PROVIDER: S-EPMC6273603 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Bharathiraja Subramaniyan S Seo Hansu H Manivasagan Panchanathan P Santha Moorthy Madhappan M Park Suhyun S Oh Jungwan J
Molecules (Basel, Switzerland) 20161103 11
C-phycocyanin, a natural blue-colored pigment-protein complex was explored as a novel photosensitizer for use in low-level laser therapy under 625-nm laser illumination. C-phycocyanin produced singlet oxygen radicals and the level of reactive oxygen species (ROS) were raised in extended time of treatment. It did not exhibit any visible toxic effect in the absence of light. Under 625-nm laser irradiation, c-phycocyanin generated cytotoxic stress through ROS induction, which killed MDA-MB-231 brea ...[more]