Ontology highlight
ABSTRACT:
SUBMITTER: Till U
PROVIDER: S-EPMC6273951 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Till Ugo U Gibot Laure L Mingotaud Anne-Françoise AF Ehrhart Jérôme J Wasungu Luc L Mingotaud Christophe C Souchard Jean-Pierre JP Poinso Alix A Rols Marie-Pierre MP Violleau Frédéric F Vicendo Patricia P
Molecules (Basel, Switzerland) 20161130 12
Drug delivery by nanovectors involves numerous processes, one of the most important being its release from the carrier. This point still remains unclear. The current work focuses on this point using poly(ethyleneglycol-b-ε-caprolactone) micelles containing either pheophorbide-a (Pheo-a) as a fluorescent probe and a phototoxic agent or fluorescent copolymers. This study showed that the cellular uptake and the phototoxicity of loaded Pheo-a are ten times higher than those of the free drug and reve ...[more]