Tandem Catalysis of an Aldol-'Click' Reaction System within a Molecular Hydrogel.
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ABSTRACT: A heterogeneous supramolecular catalytic system for multicomponent aldol-'click' reactions is reported. The copper(I) metallohydrogel functionalized with a phenyltriazole fragment was able to catalyze the multicomponent reaction between phenylacetylene, p-nitrobenzaldehyde, and an azide containing a ketone moiety, obtaining the corresponding aldol products in good yields. A possible mechanistic pathway responsible for this unexpected catalytic behavior has been proposed.
SUBMITTER: Araujo M
PROVIDER: S-EPMC6273958 | biostudies-literature |
REPOSITORIES: biostudies-literature
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