Involvement of Aquaporins in the Pathogenesis, Diagnosis and Treatment of Sjogren's Syndrome.
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ABSTRACT:
SUBMITTER: Soyfoo MS
PROVIDER: S-EPMC6274940 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
Involvement of Aquaporins in the Pathogenesis, Diagnosis and Treatment of Sjögren's Syndrome.
Soyfoo Muhammad Shahnawaz MS Chivasso Clara C Perret Jason J Delporte Christine C
International journal of molecular sciences 20181030 11
Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by lymphocytic infiltration of salivary and lacrimal glands resulting in diminished production of saliva and tears. The pathophysiology of SS has not yet been fully deciphered. Classically it has been postulated that sicca symptoms in SS patients are a double step process whereby lymphocytic infiltration of lacrimal and salivary glands (SG) is followed by epithelial cell destruction resulting in keratoconjunctivitis sicca and ...[more]
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