Subspecialization within default mode nodes characterized in 10,000 UK Biobank participants.
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ABSTRACT:
SUBMITTER: Kernbach JM
PROVIDER: S-EPMC6275484 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Subspecialization within default mode nodes characterized in 10,000 UK Biobank participants.
Kernbach Julius M JM Yeo B T Thomas BTT Smallwood Jonathan J Margulies Daniel S DS Thiebaut de Schotten Michel M Walter Henrik H Sabuncu Mert R MR Holmes Avram J AJ Gramfort Alexandre A Varoquaux Gaël G Thirion Bertrand B Bzdok Danilo D
Proceedings of the National Academy of Sciences of the United States of America 20181112 48
The human default mode network (DMN) is implicated in several unique mental capacities. In this study, we tested whether brain-wide interregional communication in the DMN can be derived from population variability in intrinsic activity fluctuations, gray-matter morphology, and fiber tract anatomy. In a sample of 10,000 UK Biobank participants, pattern-learning algorithms revealed functional coupling states in the DMN that are linked to connectivity profiles between other macroscopical brain netw ...[more]
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