Ontology highlight
ABSTRACT:
SUBMITTER: Khan AA
PROVIDER: S-EPMC6275727 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Khan Ammad Aslam AA Shimokawa Takashi T Strömblad Staffan S Zhang Hongquan H
Cellular & molecular biology letters 20110915 4
Kindlin-2 is a recently identified FERM and PH domain containing integrin interacting protein. Kindlin-2 is ubiquitously expressed in normal tissues. So far, much effort has been spent exploring the functional aspects of Kindlin-2. However, the transcriptional regulation of Kindlin-2 has not yet been investigated. In this study we identified and functionally characterized the promoter of the human Kindlin-2 gene. We show that the core promoter of Kindlin-2 is a 39 base pair long GC rich fragment ...[more]