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Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up.

ABSTRACT: The data presented in this article are related to the research article entitled "Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination". The rabbit model [1], [2] is an appropriate animal model for studying syphilis, a classic sexually transmitted disease (STD). Live Treponema pallidum (T. pallidum, Tp) and inactivated T. pallidum were inoculated in the backs of New Zealand rabbits. RT-PCR was performed to determine whether T. pallidum DNA could be detected in different groups. Sixty paired serum samples from patients at follow-up were tested by RPR and recombinant Tp0971-, Tp0768-, Tp0462- and Tp92-based ELISA.

SUBMITTER: Liu W

PROVIDER: S-EPMC6276544 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up.

Liu Wen W Zhang Xiaohong X Zhao Tie T Zhou Chenglong C Duan Junxia J Zhao Feijun F

Data in brief 20181107

The data presented in this article are related to the research article entitled "Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination". The rabbit model [1], [2] is an appropriate animal model for studying syphilis, a classic sexually transmitted disease (STD). Live Treponema pallidum (T. pallidum, Tp) and inactivated T. pallidum were inoculated in the backs of New Zealand rabbits. RT-PCR was performed to dete ...[more]

PMID: 30555861

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