Dataset Information

LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures.

ABSTRACT: SUMMARY:LS-SNP/PDB is a new WWW resource for genome-wide annotation of human non-synonymous (amino acid changing) SNPs. It serves high-quality protein graphics rendered with UCSF Chimera molecular visualization software. The system is kept up-to-date by an automated, high-throughput build pipeline that systematically maps human nsSNPs onto Protein Data Bank structures and annotates several biologically relevant features. AVAILABILITY:LS-SNP/PDB is available at (http://ls-snp.icm.jhu.edu/ls-snp-pdb) and via links from protein data bank (PDB) biology and chemistry tabs, UCSC Genome Browser Gene Details and SNP Details pages and PharmGKB Gene Variants Downloads/Cross-References pages.

SUBMITTER: Ryan M

PROVIDER: S-EPMC6276889 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature

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Publications

LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures.

Ryan Michael M Diekhans Mark M Lien Stephanie S Liu Yun Y Karchin Rachel R

Bioinformatics (Oxford, England) 20090415 11

<h4>Summary</h4>LS-SNP/PDB is a new WWW resource for genome-wide annotation of human non-synonymous (amino acid changing) SNPs. It serves high-quality protein graphics rendered with UCSF Chimera molecular visualization software. The system is kept up-to-date by an automated, high-throughput build pipeline that systematically maps human nsSNPs onto Protein Data Bank structures and annotates several biologically relevant features.<h4>Availability</h4>LS-SNP/PDB is available at (http://ls-snp.icm.j ...[more]

PMID: 19369493

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Dataset Information

LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures.

Publications

LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures.

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