Oxytocin-mediated social enrichment promotes longer telomeres and novelty seeking.
Ontology highlight
ABSTRACT:
SUBMITTER: Faraji J
PROVIDER: S-EPMC6277206 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Oxytocin-mediated social enrichment promotes longer telomeres and novelty seeking.
Faraji Jamshid J Karimi Mitra M Soltanpour Nabiollah N Moharrerie Alireza A Rouhzadeh Zahra Z Lotfi Hamid H Hosseini S Abedin SA Jafari S Yaghoob SY Roudaki Shabnam S Moeeini Reza R Metz Gerlinde As GA
eLife 20181113
The quality of social relationships is a powerful determinant of lifetime health. Here, we explored the impact of social experiences on circulating oxytocin (OT) concentration, telomere length (TL), and novelty-seeking behaviour in male and female rats. Prolonged social housing raised circulating OT levels in both sexes while elongating TL only in females. Novelty-seeking behaviour in females was more responsive to social housing and increased OT levels than males. The OT antagonist (OT ANT) L-3 ...[more]
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