Ontology highlight
ABSTRACT:
SUBMITTER: Gangalum RK
PROVIDER: S-EPMC6277220 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Gangalum Rajendra K RK Kim Dongjae D Kashyap Raj K RK Mangul Serghei S Zhou Xinkai X Elashoff David D Bhat Suraj P SP
iScience 20181117
The developing eye lens presents an exceptional paradigm for spatial transcriptomics. It is composed of highly organized long, slender transparent fiber cells, which differentiate from the edges of the anterior epithelium of the lens (equator), attended by high expression of crystallins, which generates transparency. Every fiber cell, therefore, is an optical unit whose refractive properties derive from its gene activity. Here, we probe this tangible relationship between the gene activity and th ...[more]