Ontology highlight
ABSTRACT:
SUBMITTER: Aspatwar A
PROVIDER: S-EPMC6278287 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20181108 11
Mycobacteria cause a variety of diseases, such as tuberculosis, leprosy, and opportunistic diseases in immunocompromised people. The treatment of these diseases is problematic, necessitating the development of novel treatment strategies. Recently, β-carbonic anhydrases (β-CAs) have emerged as potential drug targets in mycobacteria. The genomes of mycobacteria encode for three β-CAs that have been cloned and characterized from <i>Mycobacterium tuberculosis</i> (Mtb) and the crystal structures of ...[more]