Sex differences in Alzheimer's disease and common neuropathologies of aging.
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ABSTRACT:
SUBMITTER: Oveisgharan S
PROVIDER: S-EPMC6279593 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Publications
Sex differences in Alzheimer's disease and common neuropathologies of aging.
Oveisgharan Shahram S Arvanitakis Zoe Z Yu Lei L Farfel Jose J Schneider Julie A JA Bennett David A DA
Acta neuropathologica 20181017 6
Alzheimer's dementia is significantly more common in women than in men. However, few pathological studies have addressed sex difference in Alzheimer's disease (AD) and other brain pathologies. We leveraged postmortem data from 1453 persons who participated in one of two longitudinal community-based studies of older adults, the Religious Orders Study and the Rush Memory and Aging Project. Postmortem examination identified AD pathologies, neocortical Lewy bodies, DNA-binding protein 43 (TDP-43), h ...[more]
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