Ontology highlight
ABSTRACT:
SUBMITTER: Sander AL
PROVIDER: S-EPMC6280709 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Sander Anna-Lena AL Corman Victor Max VM Lukashev Alexander N AN Drexler Jan Felix JF
Cold Spring Harbor perspectives in medicine 20181203 12
The enterically transmitted hepatitis A (HAV) and hepatitis E viruses (HEV) are the leading causes of acute viral hepatitis in humans. Despite the discovery of HAV and HEV 40-50 years ago, their evolutionary origins remain unclear. Recent discoveries of numerous nonprimate hepatoviruses and hepeviruses allow revisiting the evolutionary history of these viruses. In this review, we provide detailed phylogenomic analyses of primate and nonprimate hepatoviruses and hepeviruses. We identify conserved ...[more]